At the end of 2022 Kieran Pocknell started his PhD with Professor Nicola Mutch at the University of Aberdeen in collaboration with the Synapse Research Institute. His project aims to understand how vascular endothelial cells dictate localised fibrinolytic potential and become perturbed during thromboinflammatory conditions. So far, he has worked with Synapse in testing and standardising the sensitivity of a novel plasmin generation assay, developed at Synapse, to various fibrinolytic inhibitors. The overall aim is to incorporate vascular endothelial cells alongside platelet rich plasma into this assay, to better represent and understand in vivo plasmin generation.
Kieran completed his Bachelor of Science in Immunology and Pharmacology at the University of Aberdeen, after which he continued his interest in the interaction of the immune system with various cell types with a Master of Science in Immunology and Immunotherapy. After completing his Master of Science Project in humanising chimeric mouse monoclonal antibodies he continued his interest in inflammatory impact on cellular function when started his PhD in Professor Nicola Mutch’s lab.